En
  • دکتری (1390)

    مهندسی شیمی

    دانشگاه صنعتی امیرکبیر،

  • کارشناسی‌ارشد (1386)

    مهندسی شیمی - بیوتکنولوژی

    دانشگاه صنعتی امیرکبیر،

  • کارشناسی (1384)

    مهندسی شیمی - طراحی فرایند

    دانشگاه علم و صنعت ایران،

  • بیوراکتورهای چند فازی برای تصفیه هوا
  • بیوتکنولوژی محیط زیست
  • مدل سازی ریاضی و شبکه عصبی مصنوعی در فرآیندهای زیستی
  • تخریب زیستی

    دکتر سید مرتضی ضمیر، کارشناسی خود را در رشته مهندسی شیمی-طراحی فرایندهای نفت در سال 1384 از دانشگاه علم و صنعت ایران و کارشناسی ارشد و دکتری خود را به ترتیب در سال های 1386 و 1390 از دانشگاه صنعتی امیرکبیر در رشته مهندسی شیمی-بیوتکنولوژی اخذ کرد. وی سپس به عنوان عضو هیات علمی به گروه مهندسی شیمی-بیوتکنولوژی دانشگاه تربیت مدرس ملحق شد. گروه تحقیقاتی وی در حال حاضر روی موضوع‌های مختلفی در حوزه بیوتکنولوژی محیط زیست مانند بیوراکتورهای چندفازی برای تصفیه هوای آلوده صنعتی، تخریب زیستی مواد خطرناک، اثر حضور نانوذرات اکسید فلزی بر فرایندهای تصفیه فاضلاب، مدل‌سازی ریاضی و شبکه عصبی مصنوعی فرایندهای زیستی مشغول به فعالیت هستند.

    ارتباط

    رزومه

    Compounds interactions during simultaneous biodegradation of hydrophobic n-hexane and hydrophilic methanol vapors in one-and two-liquid phase conditions

    Sina Keramati, Milad Ferdowsi, Seyed Morteza Zamir
    Journal PapersProcess Safety and Environmental Protection , Volume 147 , 2021 March 1, {Pages 283-291 }

    Abstract

    Simultaneous biodegradation of n-hexane (H) and methanol (M) was studied in batch culture in the concentration range of 5−10 g m−3 and 1−5 g m−3, respectively, in the absence and presence of 5−10 % v/v silicone oil. The addition of oil likely increased the mass transfer of H and ended up to H removal efficiency (REH) improvement from 72 –86 % to 92–94 %. In contrast, M removal efficiency (REM) decreased from 15-–34 % to 6–24 %, due to an increase in the M partition coefficient from 0.00018 to 0.003. Based on statistical analysis, REH and REM of 90 % and 24 % were obtained at optimum condition of 5 g m−3, 1 g m−3, and 5 % v/v for H, M, and oil fraction, respectively. Kinetic study based on Michaelis- Menten for H biodeg

    The Effect of Crop Residue on Organic Carbon and Fertility of the Soil in Wheat-Corn Rotation

    Morad Mirzaei, Manouchehr Gorji Anari, Ehsan Razavy-Toosi, Hossein Asadi, Ebrahim Moghiseh, Seyed Morteza Zamir
    Journal PapersIranian Journal of Soil and Water Research , Volume 51 , Issue 12, 2021 February 19, {Pages 3207-3219 }

    Abstract

    Addition of plant residues is an effective strategy for increasing soil nutrients, improving their use efficiency, providing better conditions for root growth and sustainable crop production. A field experiment was conducted to assess the effects of incorporation of varying rates of crop residue on the soil organic carbon and nutrients status at 0-10, and 10-20 cm soil depth, in a wheat-corn rotation under conventional tillage system. The field experiment was performed as a factorial and in the form of completely randomized block design with four replications in the farm of agricultural and natural resources college of University of Tehran for two growing years. The treatments included incorporation of five levels of crop residues (100, 75,

    The Effect of Surface Coating of Iron Oxide Nanoparticles on Magnetic Resonance Imaging Relaxivity

    Fatemeh Ahmadpoor, Atif Masoud, Neus Feliu, Wolfgang Parak, Seyed Abbas Shojaosadati
    Journal PapersFrontiers in Nanotechnology , Volume 3 , 2021 January , {Pages 13 }

    Abstract

    Iron oxide nanoparticles (IONPs) with acceptable biocompatibility and size dependent magnetic properties can be used as efficient contrast agents in magnetic resonance imaging (MRI). Herein, we have investigated the impact of particle size and surface coating on the proton relaxivity of IONPs, as well as engineering of small IONPs' surface coating as a strategy for achieving gadolinium free contrast agents. Accordingly, polymer coating using poly(isobutylene-alt-maleic anhydride) (PMA) with overcoating of the original ligands was applied for providing colloidal stability to originally oleic acid capped IONPs in aqueous solution. In case of replacement of the original ligand shell the polymer had been modified with dopamine. Furthermore, the

    Pectin/lignocellulose nanofibers/chitin nanofibers bionanocomposite as an efficient biosorbent of cholesterol and bile salts

    Alireza Chackoshian Khorasani, Fatemeh Kouhfar, Seyed Abbas Shojaosadati
    Journal PapersCarbohydrate Polymers , Volume 261 , 2021 June 1, {Pages 117883 }

    Abstract

    A new biosorbent Ca-crosslinked pectin/lignocellulose nanofibers/chitin nanofibers (PLCN) was synthesized for cholesterol and bile salts adsorption from simulated intestinal fluid during gastric-intestinal passage. The physico-chemical properties of PLCN were studied using SEM, FTIR, XRD, DSC and BET. Before gastrointestinal passage, PLCN had an amorphous single-phase, compact structure formed via hydrogen and van der Waals bonds that revealed an irregular shape with the shriveled surface but watery condition and enzymatic digestion led to create a porous structure without destruction because of the water-insoluble nanofibers, therefore increasing the adsorption capacity. The maximum adsorption capacity reached 37.9 and 5578.4 mg/g for chol

    A novel self-assembled micelles based on stearic acid modified schizophyllan for efficient delivery of paclitaxel

    Zahra Negahban, Seyed Abbas Shojaosadati, Sepideh Hamedi
    Journal PapersColloids and Surfaces B: Biointerfaces , Volume 199 , 2021 March 1, {Pages 111524 }

    Abstract

    This study was aimed to design a novel amphiphilic carrier based on schizophyllan (SPG) exopolysacharide for drug delivery. Stearic acid (SA) was used for the esterification of SPG with two degrees of substitutions (SA-SPG0.5 and SA-SPG1). The H NMR and FTIR spectroscopies verified the succesfull esterification of SPG. The polymeric micelles easily self-assembled into nanomicelles by ultrasound method. Fluorescence spectroscopy showed that the critical micelle concentrations (CMCs) of SA-SPG0.5 and SA-SPG1 micelles were 0.068 mg/mL and 0.027 mg/mL, respectively. DLS analyses showed that nanomicelles were ranged from 156 to 175 nm. SEM and TEM images showed that nanomicelles were mostly spherical. Paclitaxel (PTX) as a drug model was s

    Repetitive non-destructive extraction of lipids from Chlorella vulgaris grown under stress conditions

    Shabnam Mirizadeh, Alessandro Alberto Casazza, Attilio Converti, Mohsen Nosrati, Seyed Abbas Shojaosadati
    Journal PapersBioresource Technology , Volume 326 , 2021 April 1, {Pages 124798 }

    Abstract

    The aim of this study was the investigation of non-destructive lipid extraction from Chlorella vulgaris grown under stress conditions of nutrient limitation and salinity. To select a suitable solvent for extraction, the performances of decane, dodecane and hexadecane were tested based on their effect on lipid extraction and cell viability. The results showed that dodecane was the most suitable solvent for the extraction process. The concentration of extracted lipids from stressed cells was 2762.52???11.38?mg L−1, i.e. a value 1.75 times higher than that obtained from unstressed cells. Long-term extraction was also evaluated with continuous dodecane recirculation during five-stage extraction and a recovery time of 24?h between the extracti

    Synthesis and characterization of Schiff base containing bovine serum albumin-gum arabic aldehyde hybrid nanogels via inverse miniemulsion for delivery of anticancer drug

    Ghazal Bashiri, Seyed Abbas Shojaosadati, Mahdi Abdollahi
    Journal PapersInternational Journal of Biological Macromolecules , Volume 170 , 2021 February 15, {Pages 222-231 }

    Abstract

    The periodate modified gum arabic was used as a natural-based, non-toxic cross-linker to synthesize hybrid bovine serum albumin-gum arabic aldehyde (BSA-GAA) nanogels by Schiff base reaction through the inverse miniemulsion method for the first time. The synthesis process was performed in the absence of toxic organic solvents using fractionated coconut oil as the continuous phase. The particle size of the nanogels was managed by tweaking the concentration of the surfactants (Span 80/Tween 80) and the total volume of the aqueous phase. Based on the bicinchoninic acid method, the cross-linking efficiency of BSA and GAA was estimated at 98%. 5-fluorouracil (5-FU) was selected as the sample drug. The 5-FU-loaded hybrid nanogels showed a spheric

    Enhancement of schizophyllan production in Schizophyllum commune using microparticles in medium

    Vahid Alizadeh, Seyed Abbas Shojaosadati, Seyed Morteza Zamir
    Journal PapersBioprocess and Biosystems Engineering , Volume 44 , Issue 2, 2021 February , {Pages 317-328 }

    Abstract

    Schizophyllum commune is a wood-rotting filamentous fungus that secrets a homopolysaccharide called as schizophyllan. Schizophyllan has several applications such as enhanced oil recovery, pharmaceutical materials and an anti-cancer drug carrier. Biomass growth and schizophyllan production increase the viscosity of the cultivation medium, thus resulting in mass transfer limitation for the substrate. In this study, adding talc and aluminium oxide microparticles into the cultivation medium was studied to improve the fungal growth and morphology. The response surface methodology and one factor at a time were applied to find the effects of microparticles with different sizes and concentrations on the schizophyllan production. The optimum concent

    In situ production and deposition of nanosized zinc oxide on cotton fabric

    Taherh Mahmoudi Alashti, Negar Motakef-Kazemi, Seyed Abbas Shojaosadati
    Journal PapersIranian Journal of Chemistry and Chemical Engineering (IJCCE) , Volume 40 , Issue 1, 2021 February 1, {Pages 09-Jan }

    Abstract

    IIn this research, the cotton fabric was modified with nanosized zinc oxide (ZnO)?by a simple and novel approach. The nanosized zinc oxide was prepared and deposited onto cotton fabrics by in situ method using zinc acetate dihydrate (Zn(OAc)2.H2O) as precursors and sodium hydroxide, with and without starch as a capping agent. The size and morphology of nanosized zinc oxide?on cotton fabric in the presence and absence of starch were investigated. The samples were characterized by X-Ray Diffraction (XRD), Fourier Transform InfraRed (FT-IR) spectroscopy, Scanning Electron Microscopy (SEM), Energy-Dispersive X-ray spectroscopy (EDS), Atomic Absorption Spectroscopy (AAS), and contact angle. The antibacterial activity of modified cotton was evalu

    Removal of toluene in a biotrickling filter in the presence of methanol vapors: Experimental study, mathematical modeling, and kinetic parameters optimization

    Mohammad Kalantar, Seyed Morteza Zamir, Milad Ferdowsi, Seyed Abbas Shojaosadati
    Journal PapersJournal of Environmental Chemical Engineering , Volume 9 , Issue 1, 2021 February 1, {Pages 104617 }

    Abstract

    The performance of biotrickling filters (BTFs) has been significantly affected during the co-treatment of volatile organic compounds (VOCs) with different hydrophilicities. Removal of toluene vapor as a hydrophobic compound in the absence and presence of methanol as a hydrophilic pollutant was studied in a BTF. The inlet loading ranges were 18−36 g.m−3.h−1 for toluene and 0−225 g.m−3.h−1 for methanol at constant empty bed residence time (EBRT) of 60 s. The removal efficiency of toluene (RET) varied from 30 to 80 %, while RE of methanol (REM) remained almost constant at > 90 % within different phases of experiments due to the unlimited solubility in water. A comprehensive dynamic mathematical model consisting of mass transfer thr

    Enhanced elimination of gaseous toluene and methanol emissions in a two-liquid phase trickling bioreactor: Performance evaluation, dynamic modeling, and microbial community shift

    M Kalantar, SM Zamir, M Ferdowsi, SA Shojaosadati
    Journal Papers , , {Pages }

    Abstract

    Performance evaluation of a trickling bioreactor treating methanol vapor under one-and two-liquid phase conditions

    M Ramezani, M Khorshidizadeh, SM Zamir, M Ferdowsi
    Journal Papers , , {Pages }

    Abstract

    Removal of toluene in a biotrickling filter in the presence of methanol vapors: Experimental study, mathematical modeling, and kinetic parameters optimization

    Mohammad Kalantar, Seyed Morteza Zamir, Milad Ferdowsi, Seyed Abbas Shojaosadati
    Journal PapersJournal of Environmental Chemical Engineering , 2020 October 18, {Pages 104617 }

    Abstract

    The performance of biotrickling filters (BTFs) has been significantly affected during the co-treatment of volatile organic compounds (VOCs) with different hydrophilicities. Removal of toluene vapor as a hydrophobic compound in the absence and presence of methanol as a hydrophilic pollutant was studied in a BTF. The inlet loading ranges were 18-36 g.m-3. h-1 for toluene and 0-225 g.m-3. h-1 for methanol at constant empty bed residence time (EBRT) of 60 s. The removal efficiency of toluene (RET) varied from 30 to 80 %, while RE of methanol (REM) remained almost constant at > 90 % within different phases of experiments due to the unlimited solubility in water. A comprehensive dynamic mathematical model consisting of mass transfer thr

    Enhancement of schizophyllan production in Schizophyllum commune using microparticles in medium

    Vahid Alizadeh, Seyed Abbas Shojaosadati, Seyed Morteza Zamir
    Journal PapersBioprocess and Biosystems Engineering , 2020 September 21, {Pages 12-Jan }

    Abstract

    Schizophyllum commune is a wood-rotting filamentous fungus that secrets a homopolysaccharide called as schizophyllan. Schizophyllan has several applications such as enhanced oil recovery, pharmaceutical materials and an anti-cancer drug carrier. Biomass growth and schizophyllan production increase the viscosity of the cultivation medium, thus resulting in mass transfer limitation for the substrate. In this study, adding talc and aluminium oxide microparticles into the cultivation medium was studied to improve the fungal growth and morphology. The response surface methodology and one factor at a time were applied to find the effects of microparticles with different sizes and concentrations on the schizophyllan production. The optimum concent

    Effect of crop residue on soil organic carbon content and fertility in wheat-corn rotation

    Morad Mirzaei, Manouchehr Gorji Anari, Ehsan Razavy-Toosi, Hossein Asadi, Ebrahim Moghiseh, Seyed Morteza Zamir
    Journal PapersIranian Journal of Soil and Water Research , 2020 November 7, {Pages }

    Abstract

    Addition of plant residue is an effective strategy for increasing soil nutrient status, improve their use efficiency, providing better conditions for root growth, and sustainable crop production. A field experiment was conducted to assess the effects of incorporation of varying rates of crop residue on the soil organic carbon and nutrients status at 0-10, and 10-20 cm soil depth, in a wheat-corn rotation under conventional tillage system. The treatments included incorporation of five levels of crop residue (100, 75, 50, 25 and 0%), added following wheat and corn in the rotation. The results showed that more added residue resulted in stronger effects on the measured properties. In most cases, the maximum residue level (100%) resulted in grea

    Enhancement of extracellular bispecific anti‐MUC1 nanobody expression in E. coli BL21 (DE3) by optimization of temperature and carbon sources through an?…

    Leila Rezaei, Seyed Abbas Shojaosadati, Leila Farahmand, Shima Moradi‐Kalbolandi
    Journal PapersEngineering in Life Sciences , Volume 20 , Issue 8, 2020 August , {Pages 338-349 }

    Abstract

    Escherichia coli is one of the most suitable hosts for production of antibodies and antibody fragments. Antibody fragment secretion to the culture medium improves product purity in cell culture and diminishes downstream costs. In this study, E. coli strain BL21 (DE3) harboring gene encoding bispecific anti‐MUC1 nanobody was selected, and the autoinduction methodology for expression of bispecific anti‐MUC1 nanobody was investigated. Due to the replacement of IPTG by lactose as inducer, less impurity and toxicity in the final product were observed. To increase both intracellular and extracellular nanobody production, initially, the experiments were performed for the key factors including temperature and duration of protein expression. Th

    Mussel-Inspired Magnetic Nanoflowers as an Effective Nanozyme and Antimicrobial Agent for Biosensing and Catalytic Reduction of Organic Dyes

    Mahsa Mohammad, Fatemeh Ahmadpoor, Seyed Abbas Shojaosadati
    Journal PapersACS omega , Volume 5 , Issue 30, 2020 July 20, {Pages 18766-18777 }

    Abstract

    Mussel-inspired chemistry has been embodied as a method for acquiring multifunctional nanostructures. In this research, a novel mussel-inspired magnetic nanoflower was prepared through a mussel-inspired approach. Herein, magnetic PDA–Cu nanoflowers (NFs) were assembled via incorporating magnetic Fe3O4@SiO2–NH2 core/shell nanoparticles (NPs) into mussel-inspired polydopamine (PDA) and copper phosphate as the organic and inorganic portions, respectively. Accordingly, the flower-like morphology of MNPs PDA–Cu NFs was characterized by scanning electron microscopy (SEM) images. X-ray diffraction (XRD) analysis confirmed the crystalline structure of magnetic nanoparticles (MNPs) and copper phosphate. Vibrating sample magnetometer (VSM) data

    Efficient butanol production under aerobic conditions by coculture of Clostridium acetobutylicum and Nesterenkonia sp. strain F

    Ehsan Ebrahimi, Hamid Amiri, Mohammad A Asadollahi, Seyed A Shojaosadati
    Journal PapersBiotechnology and bioengineering , Volume 117 , Issue 2, 2020 February , {Pages 392-405 }

    Abstract

    Clostridium acetobutylicum is widely used for the microbial production of butanol in a process known as acetone–butanol–ethanol (ABE) fermentation. However, this process suffers from several disadvantages including high oxygen sensitivity of the bacterium which makes the process complicated and necessitate oxygen elimination in the culture medium. Nesterenkonia sp. strain F has attracted interests as the only known non‐Clostridia microorganism with inherent capability of butanol production even in the presence of oxygen. This bacterium is not delimited by oxygen sensitivity, a challenge in butanol biosynthesis, but the butanol titer was far below Clostridia. In this study, Nesterenkonia sp. strain F was cocultivated with C. acetobuty

    A comparative study on schizophyllan and chitin nanoparticles for ellagic acid delivery in treating breast cancer

    Shirin Pirzadeh-Naeeni, Mohammad Reza Mozdianfard, Seyed Abbas Shojaosadati, Alireza Chackoshian Khorasani, Tayebeh Saleh
    Journal PapersInternational journal of biological macromolecules , Volume 144 , 2020 February 1, {Pages 380-388 }

    Abstract

    In this study, following encapsulation of ellagic acid (EA), an anti-cancer agent, loaded in schizophyllan (EA/SPG-NP) and chitin (EA/Ch-NP) nanoparticles, its release in 95% ethanol, and different mediums of digestive systems with pH ranging 1.5 to 7.4, were examined before investigating for treatment of breast cancer MCF-7cells. Following synthesis, the EA was characterized by FT-IR, SEM, XRD, DLS and zeta potential analysis. Loading capacity of schizophyllan and chitin were 30.08 and 79.52%, respectively, while SEM images indicated respective size distributions of 217.8 and 39.82?nm, with the corresponding zeta potentials being +27 and −9.14?mV. As EA was loaded in nanoparticles, antioxidant activity, examined by DPPH method, of the fr

    Bio-removal of Heavy Metalsusing Iron-oxidizing Bacteria: A Novel Approach in Environmental Biotechnology

    Sareh Farahani, Abbas Akhavan Sepahi, Seyed Abbas Shojaosadati, Farzaneh Hosseini
    Journal PapersIranian Journal of Pharmaceutical Research: IJPR , Volume 19 , Issue 3, 2020 January , {Pages 421 }

    Abstract

    The pharmaceutical and hygienic productivity of wastewater containing pollutants, especially heavy metals such as nickel, andmercury are brought into the nature. Recently, bio-removal of heavy metals has attracted significant attention as an eco-friendly approach for the research departments of the pharmaceutical companies. In the current study, removal of heavy metals including mercury and nickel was assessed using isolatediron-oxidizing bacteria from different sources. To this end, bacterial populations were isolated from a variety of aquatic ecosystems; including Mahallat Pond, mountainous rivers, iron industry wastewater, and treated industrial wastewater. The bacteria were cultured and purified in iron-oxidizing media after which the r

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    دروس نیمسال جاری

    • كارشناسي ارشد
      بيوتكنولوژي محيط زيست ( واحد)
      دانشکده مهندسی شیمی، گروه مهندسي شيمي - بيوتكنولوژي

    دروس نیمسال قبل

    • كارشناسي ارشد
      پديده هاي انتقال درسامانه هاي زيستي ( واحد)
      دانشکده مهندسی شیمی، گروه مهندسي شيمي - بيوتكنولوژي
    • 1400
      تقي پورماكوئي, فربد
      مطالعه تخريب زيستي تركيبات فنولي و توليد انرژي در يك پيل سوختي ميكروبي
    • 1400
      عباسي, معين
    • 1401
      هوشمند, صابر
    • 1396
      اميربنده, مهكامه
      اثر حضور نانوذرات اكسيد سريم بر فرآيند تصقيه فاضلاب در يك زيست واكنشگاه چكنده
    • 1398
      برگستاني, محسن
    • 1399
      پاشايي مرني, الناز
    • 1400
      كرامتي اصل شهريور, سينا
    • معاون پژوهشی و فناوری واحد بین الملل دانشگاه. از 1396
    • نماینده دانشکده مهندسی شیمی در شورای ایمنی، بهداشت و محیط زیست دانشگاه- از 1395 تا 1397
      داده ای یافت نشد

    مهم

    جدید

      اطلاعیه ای درج نشده است